Treating the issues with Diet

Food Insecurity!

What can I eat without hurting? that will help cure me?

Building a new diet considering everything together. 


FACTS:

The Dx is; 

These tests reveal a comprehensive look at the GI tract in my body. The gastritis and mild inflammation in the Upper GI. The polyps, abnormal mucosa, and diverticulum found throughout the colon. The dysbiosis of the gut bacteria.

inflamed gut as characterized by IBS,IBD, Crohn's (blood test AMCA, GI Assay test, experience)

Diverticulosis and inflammation of gut as observed by the endo and colonoscopy.
Ulcerated mucosa in the terminal ileum

Dysbiosis of Gut microbiome from (GI Assay)


this rings similar to tests in the past that showed inflammation in a number of areas. but here the pathology has expressed itself around the colon. 

Issue:

How to treat these many symptoms and pathologies? Which to treat first? Are they related? 

hypothetically, the symptoms are all related. I have had gut problems since the age of 8ish. They have expressed themselves in a number of ways. Gastritis, peptic ulcer disease, nausea, abdominal pain, Anxiety, depression, IBS, IBD, Crohns, Diverticula, abnormal mucosa. A question for the scholars is, 1. are the mental pathologies causing the symptoms, or are 2. the psychological issues symptoms of the pain, or 3. even unrelated to the genesis of the pain. To me they seem intertwined, but not in the way I've been told or is commonly understood.  

There is a question of whether my mental state (stress, anxiety, depression) is causing the chronic inflammation which appears as various evolving pathologies? Or vice versa, the chronic inflammation takes a toll on my mental state and produces mental dysfunctions. Am I being alerted, or designing and directing?

I have come to the hypothesis that the human biome has a huge influence on the physiology and psychology of an individual, based on all the papers that say the microbiome is at least partly responsible. Further, some constituents that make up the microbiome have been found to be linked for neuropathies like anxiety and depression. 

It's possible that my microbiome has been out of whack for decades, leading to inflammation, which evolves to pathologies. The negative actors in this biome producing metabolites that create inflammation in the gut and mind that over time get exacerbated to the point of irreversible damage (diverticula).

or it's possible that the dysbiosis is not causing the pathologies and is merely a symptom. In that case treating the dysbiosis is still necessary. 

"You are what you eat"



"your body is your temple"




Rule:

Treatments: There is not much consensus on how to effectively treat IBD, Crohn's, Diverticulosis, Dysbiosis, or why they occur, or when they will occur. 

Doctors treat Crohn's disease with medicines, bowel rest, and surgery. No single treatment works for everyone with Crohn's disease. The goals of treatment are to decrease the inflammation in your intestines, to prevent flare-ups of your symptoms, and to keep you in remission.

Treatment for Crohn’s Disease (2022). Available at: https://www.niddk.nih.gov/health-information/digestive-diseases/crohns-disease/treatment (Accessed: 17 August 2022).

The goal of inflammatory bowel disease treatment is to reduce the inflammation that triggers your signs and symptoms. In the best cases, this may lead not only to symptom relief but also to long-term remission and reduced risks of complications. IBD treatment usually involves either drug therapy or surgery. 

Inflammatory bowel disease (IBD) (2022). Available at: https://www.mayoclinic.org/diseases-conditions/inflammatory-bowel-disease/diagnosis-treatment/drc-20353320 (Accessed: 17 August 2022).

 If diverticula cause chronic symptoms, your doctor may recommend one or more treatments, such as

  • high-fiber foods or fiber supplements
  • antibiotics NIH external link
  • medicines to reduce inflammation
  • probiotics NIH external link


 

Treatment for Diverticular Disease (2022). Available at: https://www.niddk.nih.gov/health-information/digestive-diseases/diverticulosis-diverticulitis/treatment (Accessed: 17 August 2022). 


At the heart of the inflammatory process in IBD is “dysbiosis” of the gut microbiome, which may be driven by host genetics and environmental factors like diet.
Hold GL, Smith M, Grange C, Watt ER, El-Omar EM, Mukhopadhya I. Role of the gut microbiota in inflammatory bowel disease pathogenesis: What have we learnt in the past 10 years? World J Gastroenterol 2014; 20(5): 1192-1210 [PMID: 24574795 DOI: 10.3748/wjg.v20.i5.1192]

Even our pets get the same advice, regarding dysbiosis:

Dietary modifications should always be the first treatment option. A highly digestible diet reduces undigested nutrients in the GI lumen, reducing the potential for excessive bacterial proliferation. In dogs and cats with CE, a novel or hydrolyzed protein diet reduces pro-inflammatory host responses that occur when the immune system is sensitized against the food antigen.

CANINE AND FELINE MICROBIOTA DYSBIOSIS INDEX (2022). Available at: https://vetmed.tamu.edu/gilab/service/assays/canine-microbiota-dysbiosis-index/ (Accessed: 17 August 2022). 

Application



One thing in common is that changing the diet to subsist of whole foods is the first thing that tests show offers respite. Doing this in conjunction with the low fodmap diet builds on the elimination diet, subtracting the fodmap sugars. Finally, to treat the dysbiosis, I will call on the 5R; Remove problem foods, replace, re inoculate, repair, rebalance. 



Synbiotics through supplementation 

This hybrid diet has been shown to improve the symptoms of an analogous case that I might be connecting liberally, however without more data this case is close in symptoms, understanding , and treatment:

The Successful Management Of Ulcerative Colitis With A Nutritional Intervention: A Case Report (2022). Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219448/ (Accessed: 18 August 2022).


Remove foods, chemicals and replace:


In a hybrid with the Elimination Diet (started Jun 3) and considering Low Fodmap diet, (merged August 3) I will eat a diet where I can challenge new foods that are low fodmap, including low fodmap fiber, and largely plant based. the point of the diet is to build up a new vocabulary of foods I can eat indefinitely after they have been thoughtfully considered, challenged and ultimately adding them to diet. The idea is to rule out the possibility of foods causing or exacerbating the issue.

several of the diets that are popular, especially the low-FODMAP diet and the IBD-AID, seem to be reasonably balanced and sound without causing weight loss in ill IBD patients.

Diet and Inflammatory Bowel Disease (2022). Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843040/ (Accessed: 18 August 2022). 






Re inoculate:

Further I will supplement my diet with probiotics, according to the GI assay, 350 Billion CFU a day. I will do this for first 7 days, and then 130 Billion CFU daily. (started 8/16/22) 

This will work in conjunction with a diet of home fermented foods, eating a lacto fermented food alongside every meal (as much as possible), and drinking fermented drinks. By offering a compendious variation of beneficial bacteria and yeast, I will hopefully starve the negative organisms out of the biome. 

Repair: Using the supplements recommended from the GI Assay reference, and checking them against peer reviewed articles, and adding or subtracting supplements based on new knowledge acquired. I will begin repairing the gut using this new supplement regimen as soon as possible.


If Flareups occur, I will restrict the diet even further to meet the theme of the Anti Inflammatory Diet, which relies on pureeing foods, removing all seeds, and more.


Repair:

Anti Inflammatory Diet ,
"Diet and Inflammatory Bowel Disease". Www.Ncbi.Nlm.Nih.Gov, 2022, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843040/. Accessed 17 Aug 2022.


The IBD-AID has 5 basic components: (1) the modification of specific carbohydrates (eg, refined or processed complex carbohydrates and lactose); (2) emphasis on restoring the intestinal flora balance through ingestion of prebiotics and probiotics in the form of soluble fiber such as leek, onion, and fermented foods; (3) focus on decreasing total and saturated fats, eliminating hydrogenated oils, and encouraging the increase in food sources rich in omega-3 fatty acids; (4) review of the overall dietary pattern, identification of food triggers and intolerances, and detection of missing nutrients; and (5) food texture modification to enhance absorption and reduce intact fiber.






In terms of "Flare-ups" this is the regimen the diet will transition to while still respecting low fodmap foods, "normal"







https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843040/



Re-Balance



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Reference for diet construction

Portions:


Using the harvard "healthy eating plate" as a guide for the diet






Make most of your meal vegetables and fruits – ½ of your plate.

Aim for color and variety, and remember that potatoes don’t count as vegetables on the Healthy Eating Plate because of their negative impact on blood sugar.

Go for whole grains – ¼ of your plate.

Whole and intact grains—whole wheat, barley, wheat berries, quinoa, oats, brown rice, and foods made with them, such as whole wheat pasta—have a milder effect on blood sugar and insulin than white bread, white rice, and other refined grains.

Protein power – ¼ of your plate.

Fish, poultry, beans, and nuts are all healthy, versatile protein sources—they can be mixed into salads, and pair well with vegetables on a plate. Limit red meat, and avoid processed meats such as bacon and sausage.

Healthy plant oils – in moderation.

Choose healthy vegetable oils like olive, canola, soy, corn, sunflower, peanut, and others, and avoid partially hydrogenated oils, which contain unhealthy trans fats. Remember that low-fat does not mean “healthy.”

Drink water, coffee, or tea.

Skip sugary drinks, limit milk and dairy products to one to two servings per day, and limit juice to a small glass per day.


Reproduction of diet and regimen for others:

It will open the doors to more “personalized” therapeutic interventions, which would encompass the host genotype and serotype, the disease phenotype, the gene expression profiles of the immune cells and the microbiome composition to decide the best strategy for treating patients with

Hold GL, Smith M, Grange C, Watt ER, El-Omar EM, Mukhopadhya I. Role of the gut microbiota in inflammatory bowel disease pathogenesis: What have we learnt in the past 10 years? World J Gastroenterol 2014; 20(5): 1192-1210 [PMID: 24574795 DOI: 10.3748/wjg.v20.i5.1192]


 LowFodmap Fiber Sources and max serving size:


Bulgar, uncooked 1/4 cup (44g)

Lentil, Green, Boiled 1/4 cup (23g)

Almond with skin 10 nuts (12g)

Sunflower seed 2 teaspoons (6g)

Sun-dried Tomato 3 pieces (8g)


Banana, common, unripe 1 medium (100g)

Green bean 15 beans (75g)

Red Capsicum 1/4 of 1 medium (75g)

Canned chickpea, drained 1/4 cup (42g)

Corn, fresh on cob 1/2 cob (38g)

Eggplant, unpeeled 1 cup (75g)

Goji berry, dried 3 teaspoons (10g)

Kale 1/2 cup chopped (75g)

Mandarin, peeled 2 small, peeled (125g)

Almond meal 1/4 cup (24g)

Hazelnut 10 nuts (15g)

Peanut 32 nuts (28g)

Walnut 10 nut halves (30g)

Potato, unpeeled 1/2 medium (75g)

Silverbeet 1 ½ cups chopped (75g)


Broccoli, fresh, raw, whole 3/4 cup (75g)

Carrot, mature, peeled, fresh, raw 1 medium (75g)

Kiwifruit, gold, peeled, raw 2 small, peeled (150g)

Nut, brazil, raw or blanched 10 nuts (40g)

Nut, macadamia, raw 20 nuts (40g)

Orange, peeled, raw 1 medium (130g)

Parsnip, peeled, fresh, raw 1 medium (75g)

Pineapple (cayenne), peeled, raw 1 cup chopped (140g)

Pomegranate, peeled, raw 1/4 cup seeds (45g)

Quinoa, cooked in water 1 cup cooked (155g)

Raspberry, raw 30 berries (60g)

Rhubarb, stalk, raw 1 cup chopped (150g)

Rice, brown, boiled 1 cup cooked (180g)

Spinach, baby, fresh, raw 1.5 cup chopped (75g)


Seed, linseed or flaxseed 1 tablespoon (15g)

Tahini, sesame seed pulp, unhulled 2 tablespoons (30g)


Coconut, fresh, mature fruit, flesh 2/3 cup (64g)

Noodle, soba, dry 1/3 cup (90g)

Oats, rolled, uncooked 1/2 cup (52g)


Kiwifruit, green, peeled, raw 2 small, peeled (150g)

Passionfruit, raw 2 fruits (46g)

Tofu, firm 2/3 cup cubed (160g)


Buckwheat groats, cooked 3/4 cup cooked (135g)


Seed, chia, dried 2 tablespoons (24g)

Popcorn, commercial ½ packet – 3.5 cups (60g)